I've converted my primary computer to Vista and Office 2007.  So far I'm pretty happy but I've been told the new OS smell wears off really quickly.

I've had some fun with a couple issues.  The best issue is my external display.  I'm running a Dell Inspiron 9400 with ATI Radeon Mobility X1400.  I have a dock that I sit my laptop on and have an external display that sits to the left of my laptop.  When I sign onto my computer, Vista always sets my external monitor to the right of my primary display rather than the left.

When I go into my settings and move the monitor back to the left, it works correctly until I have to log into my machine again (when I come into the office in the morning, get back to my desk after a meeting, my screen saver comes on...)

There are plenty of people out there with this issue (google: vista external display switch sides).  A comment by J. Quick on Rick Strahl's blog suggests that the issue is caused by TMM or Transient Multi-Monitor Manager.  This is a task you can find running in the Task Scheduler.

Following Quick's advice, I disabled the TMM job and killed the one that was running and then even rebooted but this didn't fix my problem.  I guess I'll keep searching... 

Read the complete post at http://ooto.info/archive/2007/09/20/Fun-with-Vista.aspx